Choosing an Optical Connection

Opto I_vs_II_Acute

In addition to specifying an electrical connector, you should also specify an optical connector when configuring an optoelectrode. NeuroNexus offers two kinds of optical connection. LEFT: The Standard optoelectrode connection uses our locking NNc coupling mechanism. RIGHT: The Low Profile (LP) optoelectrode uses ferrule-to-ferrule coupling.


Standard (NNc coupling): OA, OCM, OZ

Our custom NNc coupling mechanism offers a robust optical connection that is best suited for behavioral studies. Due to its unique locking mechanism, NNc optoelectrodes offer the most consistent optical transmission for awake behaving animals. Typical transmission from a 50 µm core patch cord to a 105 µm core optoelectrode is >80%.


Low Profile (bare ferrule-to-ferrule coupling): OA LP, OCM LP, OZ LP

Bare ferrule-to-ferrule coupling is the most commonly used tool for optogenetics studies. It offers a simplified connection and smaller package size, but lacks the secure, robust connection the NNc coupling method provides. The LP packages also mate with TDT's Motorized Commutator. Typical transmission from a 50 µm core patch cord to a 105 µm core optoelectrode is >75%. LP packages use a 1.25mm ceramic ferrule.


For stimulation only, use an implantable fiber.

Specifications - Optoelectrodes

Fiber Fused silica, 105 µm core, multi-mode
Outer Diameter 125 µm (105 µm core)
Weight (Coupler) < 0.5 g
Numerical Aperture


Durability < 5% transmission variability after 40 connections
Rotation Test < 2% variation over 1 rotation
Connection Strength > 300 g before latch separation (typical)
Max. Shear Force 900 g (applied to top of female coupler)
Length Tolerance ± 500 µm
Fiber Tip Profile Flat
Note Internal reference site is disconnected as standard. Certain designs may allow ref. site connection; contact us for specifics.

OptrodeHowTo Video RS-01

How to Order a NeuroNexus Optrode

Learn about all the options available to you when ordering a NeuroNexus Optrode.