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Science Update

Multi-Unit Activity contains information about spatial stimulus structure in mouse primary visual cortex

Publication Details

Featured Authors

Marie Tolkiehn

Simon R. Schultz

Other Publisher Name
Conference Proceedings of the IEEE Engineering in Medicine and Biology Society
Experiment Type
Acute
Animal Model
Mouse
Brain Region
Cortex Visual
Brain Signal
Multi Unit
Product Category
  • Penetrating Electrode
Product
  • A4x8-5mm-100-200-177
Abstract
This study investigates the spatial and directional tuning of Multi-Unit Activity (MUA) in mouse primary visual cortex and how MUA can reflect spatiotemporal structures contained in moving gratings. Analysis of multi-shank laminar electrophysiological recordings from mouse primary visualcortex indicates a directional preference for moving gratings around 180°, while preferred spatial frequency peaks around 0.02 cycles per degree, which is similar as reported in single-unit studies. Using only features from MUA, we further achieved a significant performance in decoding spatialfrequency or direction of moving gratings, with average decoding performances of up to 58.54% for 8 directions, and 44% correctly identified spatialfrequencies against chance level of 16.7%.
Citation
Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3771-4. doi: 10.1109/EMBC.2015.7319214.
Publication Date
08/ 1/2015
Country
United Kingdom
Institution
Imperial College London